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Wie findet man die Facility im Biozentrum

How can you work together with StruBiTEM?

Our mission is to give you the opportunity to solve your scientific question using state-of-the-art cryo-EM. Whether you are a student, postdoc, or PI, whether you are new to electron microscopy or already have experience, we will guide you step by step through your project and support you with our expertise, providing you with the necessary materials and microscopes. The collaboration is tailored to your project and its requirements. Depending on the project phase, there are different ways to work with us—from the initial idea to the interpretation of your high-resolution structure.

We look forward to your inquiry.

New to cryo-EM? Start with level 1

Are you interested in cryo-EM but don't know where to start? No problem. We are happy to assist you in planning your project—from defining the research question and preparing the samples to collecting and analyzing the data.
Here's how to proceed:

• Fill out the project proposal (see below) and provide us with as much information as possible to help us evaluate your project.
• Send the form to strubitem-contact@uni-koeln.de
• Make an appointment with us for your first project meeting. During this meeting, we will discuss whether cryo-EM is a good method for answering your research question and, if so, what steps would follow.

Do you already have initial data? Level 2: Further development of your project

Have you already had some initial experience with cryo-EM? Perhaps you already have negative stain images of your protein or even your first cryo-EM data set? Would you now like to take the next step and work towards obtaining your high-resolution structure? Here's how to proceed:

• Fill out the Project Proposal (see below). The more information you give us, the better we can help you.
• Read and fill out the User Agreement form (see below) and sign it. Have your PI sign it as well.
• Send both forms to strubitem-contact@uni-koeln.de.
• Make an appointment with us to discuss your project.

You have ready to use grids and just need some data? Level 3: Request measurement time

You already have good data and your grids are ready to use? And now just need a little more data? Here's what to do next: 

• Fill out the Project Proposal (see below) with all the relevant data about your sample and the results you have so far. This will allow us to determine the optimal data acquisition parameters for you.
• Read and sign the User Agreement (see below). Have your PI sign it as well.
• Send both to strubitem-contact@uni-koeln.de
• We will make suggestions for possible measurement times.